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. 2023 Jan 23;18(12):957–976. doi: 10.4244/EIJ-D-22-00725

Figure 1. Patient stratification and simplified guideline recommendation.

Figure 1

Therapeutic strategies for patients with (A) symptomatic severe primary mitral regurgitation (MR) or (B) symptomatic severe secondary MR. COAPT: Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation; GDMT: guideline-directed medical therapy; HTx: heart transplantation; LVAD: left ventricular assist device; M-TEER: mitral valve transcatheter edge-to-edge repair; N: no; SMVR: surgical mitral valve repair or replacement; Y: yes