Figure 5. Simplified COAPT criteria.

Simplified COAPT criteria. Simplified in- and exclusion criteria of the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (COAPT) study. ^aBNP ≥300 pg/ml or NT-proBNP ≥1,500 pg/ml. ^bincluding MVA >4.0 cm². ^csystolic pressure ≤90 mmHg, cardiogenic shock or the need for inotropic and/or mechanical supports. ^dACC/AHA classification. ACC: American College of Cardiology; AHA: American Heart Association; BNP: B-type NP; COPD: chronic obstructive pulmonary disease; CoR: class of recommendation; ESC: European Society of Cardiology; HF: heart failure; LoE: level of evidence; LV: left ventricular; LVEF: left ventricular ejection fraction; M-TEER: mitral valve transcatheter edge-to-edge repair; NP: natriuretic peptide; NYHA: New York Heart Association; RV: right ventricular; SMR: secondary mitral regurgitation