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Effects of NPPB, L-NAME, apamin, and CyPPA on the smooth muscle contractions of the colon. A significant response was observed in the proximal segment compared to that in the narrow segment after the administration of (A) NPPB, (B) L-NAME, (C) Apamin, and (D) CyPPA, *<0.05 vs. before drugs; #<0.05 vs. proximal segment.
