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. 2023 Jan 23;22:14. doi: 10.1186/s12933-023-01748-0

Table 2.

Logistics regression analysis of factors associated with CAD

Characteristics Univariable Multivariable
OR 95%CI p OR 95%CI p
Age 1.054 1.017–1.092 0.004 1.117 1.029–1.213 0.009
Gender 1.454 0.755–2.801 0.263
BMI 0.990 0.904–1.084 0.832
Obesity 0.664 0.313–1.408 0.286
Smoking 1.350 0.623–2.927 0.447
Drinking 1.935 0.669–5.594 0.223
Hypertension 2.013 1.027–3.946 0.042 2.974 0.748–11.821 0.122
Dyslipidaemia 3.349 0.932–12.035 0.064
Family history 3.667 0.791–17.003 0.097
Time since T2DM diagnosis 1.145 1.076–1.219  < 0.001 1.086 0.973–1.212 0.138
Aspirin 1.719 0.335–8.81 0.516
Statin 1.106 0.566–2.159 0.768
Metformin 1.231 0.642–2.361 0.532
Insulin 0.641 0.333–1.234 0.184
Oral antihyperglycemic drugs 2.023 0.865–4.730 0.104
HDL-cholesterol 0.327 0.083–1.290 0.110
LDL-cholesterol 1.523 1.014–2.288 0.043 1.208 0.508–2.872 0.670
Total cholesterol 1.236 0.985–1.551 0.067
Triglyceride 1.006 0.856–1.183 0.941
Fast glucose 1.202 1.067–1.354 0.003 1.037 0.825–1.305 0.753
HbA1c 1.505 1.197–1.894  < 0.001 1.597 1.048–2.434 0.029
Retinopathy 1.407 0.734–2.697 0.303
Neuropathy 1.208 0.326–4.470 0.778
Peripheral arterial occlusive disease 1.821 0.843–3.933 0.127
Nephropathy 0.976 0.498–1.912 0.943
CACS 1.021 1.010–1.031  < 0.001 1.020 1.006–1.034 0.003
PAT volume 1.004 1.000–1.008 0.055
CT-FFR 0.000 0.000–0.000  < 0.001 0.000 0.000–0.000  < 0.001
DS 1.038 1.024–1.052  < 0.001 0.954 0.918–0.993 0.018
RCA-PCATA 1.100 1.052–1.149  < 0.001 1.151 1.052–1.260 0.002
LAD-PCATA 1.042 1.003–1.083 0.036 0.964 0.88–1.054 0.424
LCX-PCATA 1.078 1.031–1.127 0.001 1.063 0.956–1.181 0.260

CAD coronary artery disease, OR odds ratio, 95%CI 95% confidence interval, T2DM type 2 diabetes mellitus, HDL high-density lipoprotein, LDL low-density lipoprotein, HbA1c glycated haemoglobin, CACS coronary artery calcium score, PAT pericardial adipose tissue, CT-FFR computed tomography-based fractional flow reserve, DS diameter stenosis, PCATA pericoronary adipose tissue attenuation