Table 1.
Basic information on CMR patients: control subjects versus HCM; without adverse clinical events versus with combined outcome
| Parameters | Control subjects (n = 89) | HCM population (n = 99) | p value | HCM patient without adverse clinical events (n = 81) | HCM patient with adverse clinical events (n = 18) | p value |
|---|---|---|---|---|---|---|
| Baseline and clinical | ||||||
| Age at CMR scan, years | 52.74 ± 10.03 | 55 (46, 65) | 0.200 | 51.85 ± 13.13 | 67 (62, 69) | < 0.001*** |
| Men, n, % | 67, 75.28% | 71, 71.7% | 0.581 | 61, 75.3% | 10, 55.6% | 0.092 |
| Family history, n, % | – | 31, 31.3% | – | 50, 61.7% | 12, 66.7% | 0.695 |
| Body mass index, kg/m2 | 26.40 (24.51, 28.40) | 26.40 ± 3.39 | 0.821 | 26.65 ± 3.36 | 25.28 ± 3.35 | 0.121 |
| Heart rate, beat/min | 68 (64, 75) | 66 (58, 68) | < 0.001*** | 67 (59, 71) | 60.17 ± 7.52 | 0.026* |
| Hypertension, n, % | 25, 28.1% | 62, 62.6% | < 0.001*** | 50, 61.7% | 12, 66.7% | 0.695 |
| Systolic blood pressure, mmHg | – | 150 (125, 180) | – | 150 (123, 180) | 159.17 ± 36.81 | 0.413 |
| Diastolic blood pressure, mmHg | – | 90 (77, 110) | – | 90 (77, 110) | 98.28 ± 26.47 | 0.420 |
| Diabetes mellitus, n, % | 15, 16.9% | 17, 17.2% | 0.954 | 14, 17.3% | 3, 16.7% | 1.000 |
| Smoking history, n, % | 44, 49.4% | 36, 36.4% | 0.070 | 29, 35.8% | 7, 38.9% | 0.806 |
| CAD, n, % | – | 26, 26.3% | – | 22, 27.2% | 4, 22.2% | 0.721 |
| PE, n, % | – | 0, 0% | – | 0, 0% | 0, 0% | – |
| CKD, n, % | – | 1, 1.01% | – | 1, 1.23% | 0, 0% | – |
Data were expressed as number (percentage), mean ± standard deviation, or median (interquartile range)
CAD, Coronary atherosclerotic heart disease; PE, Pulmonary embolism; CKD, Chronic Kidney Disease
“*”, “**”, and “***” reflect that the difference between groups is statistically significant
“*” represents p < 0.05; “**” represents p < 0.01; “***” represents p < 0.001