Table 2.
Motor function of SMA patients before and after treatment
| SMA type 1 | SMA type2 | SMA type 3 | |||||
|---|---|---|---|---|---|---|---|
| CHOP-INTEND | HINE-2 | RULM | HFMSE | RULM | HFMSE | 6MWT (m) | |
| Number | 6 | 6 | 20 | 22 | 6 | 5 | 5 |
| Baseline | 19.5 (11.9) | 4.0 (2.9) | 15.8 (8.7) | 12.5 (9.8) | 29.3 (4.8) | 44.2 (11.4) | 199.9 (196.7) |
| Day 63 | 20.5 (12.1) | 4.5 (3.6) | 17.6 (9.3) | 15.0 (10.6) | 32.7 (2.7) | 47.2 (11.6) | 226.3 (236.5) |
| P-value | 0.416 | 0.416 | 0.004 | 0.000 | 0.042 | 0.176 | 0.345 |
CHOP-INTEND Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorder, HINE-2 modified Hammersmith Infant Neurologic Examination-Part 2, RULM Revised Upper Limb Module, HFMSE Hammersmith Functional Motor Scale Expanded, 6MWT 6-Minute Walking test, m meters