Table 3.

OS and PFS at 18 months and 24 months using frequentist meta-analysis

Population	OS at 18 m %(95% CI)	PFS at 18 m % (95% CI)	OS at 24 m % (95% CI)	PFS at 24 m (95% CI)
≥3rd line	71.49 (68.68, 74.42)	35.37 (33.15, 37.75)	66.50 (63.54, 69.60)	28.26 (26.15, 30.55)
≥4th line	65.07 (60.84, 69.59)	31.36 (28.30, 34.75)	59.51 (55.12, 64.24)	24.13 (21.29, 27.35)
Representative cohorts ≥3rd line	70.92 (67.71, 74.29)	35.52 (33.16, 38.05)	66.45 (63.08, 69.99)	28.42 (26.18, 30.85)
Representative cohorts ≥4th line	65.07 (60.84, 69.59)	31.36 (28.30, 34.75)	59.51 (55.12, 64.24)	24.13 (21.29, 27.35)