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. 2023 Jan 23;2023(1):CD008986. doi: 10.1002/14651858.CD008986.pub4

ChiCTR1800017706 2018.

Study name Elderly patients multi‐drug management: a multicenter randomized controlled trial
Methods Cluster‐randomisation; in this study, a third‐party randomisation method was used to allocate 5 centres: 2 centres as control group and 3 centres as intervention group
Participants Inclusion criteria:
  • Aged 65 to 85 years old

  • Hypertension, hyperlipidaemia, coronary heart disease, cerebral infarction, diabetes patients in Cardiology Department, cerebral infarction ward of Neurology Department and Endocrinology Department

  • Using more than 5 oral medications for cardio‐cerebrovascular systems and diabetes

  • Patients volunteered to merge and sign the informed consent


Exclusion criteria:
  • Patients with cancer, blood system diseases and other serious diseases or life expectancy less than 1 year

  • Taking non‐cardio‐cerebrovascular or non‐diabetic drugs such as respiratory and digestive systems medications at the same time

  • Patients who stay in ICU

  • Peri‐operative patients

  • Patients with hearing loss, mental retardation, severe visual impairment and other factors that affect the quality of follow‐up

Interventions Pharmacists intervention with aid of intelligentialised medication review system
Outcomes
  • Incidence of potentially inappropriate medication use

  • Drug compliance

  • Blood pressure

  • Total cholesterol

  • Low density lipoprotein

  • Triglyceride

  • Blood glucose

Starting date January 2019
Contact information Study leader: Yan Suying; email: yansuying10@xwhosp.org; phone: +86 13708905057
Notes Chinese Clinical Trial Registry (accessed February 2020)
Trial ID: ChiCTR1800017706