JPRN‐UMIN000035265 2018.

Study name	Efficacy of medication optimization protocol for older inpatients: a randomized controlled trial
Methods	Randomised controlled trial
Participants	Inclusion criteria: Patients aged 65 years and older Exclusion criteria: Patients whose attending physicians do not agree to participate in the study
Interventions	Intervention group: a multidisciplinary team‐based medication review and de‐prescribing proposal based on STOPP/START criteria and a medication optimisation protocol Control group: usual care
Outcomes	Primary outcomes: composite of death, unscheduled visits, and re‐hospitalisation until 12 months after randomisation
Starting date	March 2019
Contact information	Scientific contact: Ie Kenya, Kawasaki city, Kanagawa, Japan. Email: iekenya0321@gmail.com
Notes	Trial ID: UMIN000035265