NCT04028583 2019.

Study name	Tool for Inappropriate Prescription Evaluation: The TaIPE Study (TaIPE)
Methods	Randomised controlled trial
Participants	Setting: Centre Hospitalier Universitaire Vaudois Inclusion criteria: all patients meeting the admission criteria of the acute care for elders (ACE) unit will be eligible Exclusion criteria: none
Interventions	Intervention group: PIM‐Check In the PIM‐Check group, a medication review will be conducted using PIM‐Check within 72 hours of the patient's admittance to the unit. The physician will decide whether to accept these recommendations or not and implement prescribing changes if agreed. Active comparator group: STOPP/START group In the STOPP/START group, medication lists will be analysed within 72 hours of patient's admittance and optimised according to STOPP/START criteria. The second physician will decide whether to accept these recommendations or not and implement prescribing changes if agreed.
Outcomes	Primary outcome: Rate of potentially inappropriate prescriptions (PIPs) reduction in the PIM‐Check group compared to STOPP/START (time frame: 18 months) Secondary outcomes: Number and type of PIPs detected by each tool (time frame: 18 months) Rate of acceptability (time frame: 18 months) Number of treatment (mean and median) modifications by clinicians (time frame: 18 months) Number of drugs at discharge (time frame: 18 months) The incidence rate of falls (time frame: 18 months) Activities of daily living (ADL) score (time frame: 18 months) Confusion Assessment Method (CAM) (time frame: 18 months) Length of stay (time frame: 18 months) Number of unplanned readmissions (time frame: Up to 3 months after discharge) Association between the number and type of PIPs at discharge with the rate of re‐admission (time frame: Up to 3 months after discharge)
Starting date	February 2018
Contact information	Akram Farhat, PharmD, MPH, PhD, akram.farhat@hotmail.com Chantal Csajka, PharmD, PhD +41 21 314 42 63 chantal.csajka@chuv.ch
Notes	Trial ID: NCT04028583