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. 2023 Jan 18;18:323–337. doi: 10.2147/IJN.S394896

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© 2023 Yu et al.

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(A) Scheme of the timeline for in vivo treatment and laser irradiation in 4T1-bearing orthotopic mice. (B) Tumor growth curves of mice after the treatment. (C) The images of 4T1-bearing mice with the injection of 5% glucose, DOX·HCl+ICG, PSC/ICG@ or PSC/ICG@+DOX nanoparticle after laser irradiation under the 808 nm laser irradiation (2.0 W/cm²) at 24 h post-injection. (D) Body weight change within 14 days. *P < 0.05, PSC/ICG@+DOX (NIR) group vs PSC/ICG@+DOX (no NIR) group; **P < 0.01 PSC/ICG@+DOX (NIR) group vs other groups; ^#P < 0.05, PSC/ICG@+DOX group (no NIR) vs DOX·HCl group. (n=5).