FIGURE 2:

Hazard ratios for the association between eGFR with the 2021 and 2009 CKD-EPI equation and kidney failure with replacement therapy (A), all-cause mortality (B), cardiovascular mortality (C) and major adverse cardiovascular events (D). An eGFR of 95 mL/min/1.73 m² was taken as reference value. Dotted red lines depict 95% confidence intervals for the 2021 equation, and shaded grey areas depict 95% confidence intervals for the 2009 equation. eGFR was modelled as a restricted cubic spline with five knots at the 5th, 27.5th, 50th, 72.5th and 95th percentile. Note that Y-axis is on a log-scale.