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. 2023 Jan 23;131(1):017005. doi: 10.1289/EHP11292

Table 4.

Transfer efficiencies (%) of PFAS from maternal serum at delivery into colostrum (TEC:S) and breast milk (TEB:S), stratified by exposure group.

Exposure categorya N Transfer efficiency [median (IQR)]
PFOA PFNA PFHxS PFOS
TEC:S
 Background 13 2.94 (2–3.77) 2.58 (1.78–3.1) 1.86 (1.31–2.36) 0.66 (0.4–0.92)
 Intermediate 56 2.74 (1.99–3.82) 2.60 (1.81–3.74) 1.33 (0.85–1.87) 0.76 (0.61–1.09)
 High 16 2.83 (2.57–3.65) 2.63 (2.03–3.64) 1.81 (1.23–2.27) 1.13 (0.92–1.26)
TEB:S
 Background 21 2.25 (1.82–3.45) 3.03 (2.27–3.57) 1.86 (1.39–2.36) 0.99 (0.78–1.2)
 Intermediate 68 2.18 (1.72–2.96) 2.63 (2.09–3.98) 1.12 (0.79–1.36) 1.00 (0.83–1.2)
 High 20 1.98 (1.7–2.51) 1.94 (1.57–2.89) 1.41 (1.14–1.54) 1.09 (1–1.19)

Note: Samples <LOQ were included and substituted with the LOQ divided by the square root of 2 when a measured concentration was not available. B, breast milk; C, colostrum; IQR, interquartile range; LOQ, limit of quantification; PFHxS, perfluorohexane sulfonic acid; PFNA, perfluorononanoic acid; PFOA, perfluorooctanoic acid; PFOS, perfluorooctane sulfonic acid; S, serum; TE, transfer efficiency.

a

Exposure levels were categorized based on maternal serum PFHxS concentrations (CPFHxS, ng/mL) at delivery. Background: CPFHxS0.78. Intermediate: 0.78<CPFHxS36. High: 36<CPFHxS.