Skip to main content
. Author manuscript; available in PMC: 2023 Jan 23.
Published in final edited form as: Breast Cancer Res Treat. 2022 May 3;194(1):149–158. doi: 10.1007/s10549-022-06600-9

Table 1:

Subject characteristics, hormone measures, and IGF-1/IGFBP-3 molar ratio

Variable N All women (N=316) N Parous women (N=44) N Nulliparous women (N=272)
Age at donation (years) 316 25 (21, 33) 44 35 (32, 40) 272 23 (21, 30)
Ethnicity (Hispanic/Latino) 315 9 (2.9%) 44 1 (2.3%) 271 8 (3.0%)
Race 316 44 272
 Caucasian 282 (89.2%) 37 (84.1%) 245 (90.1%)
 African American 34 (10.8%) 7 (15.9%) 27 (9.9%)
BMI 316 24.9 (22.0, 29.7) 44 27.4 (22.7, 33.3) 272 24.5 (22.0, 29.1)
Percent fat 316 60 (40, 90) 44 70 (50, 90) 272 60 (40, 80)
Current smoking 316 13 (4.1%) 44 0 (0.0%) 272 13 (4.8%)
Current drinking 315 233 (74.0%) 44 30 (68.2%) 271 203 (74.9%)
Age at first period (years) 316 12.5 (12, 13) 44 13 (12, 13) 272 12 (12, 13)
Number of live births 44 44 N/A N/A
 1 17 (38.6%) 17 (38.6%)
 2 19 (43.2%) 19 (43.2%)
 3 7 (15.9%) 7 (15.9%)
 4 0 (0.0%) 0 (0.0%)
 5 1 (2.3%) 1 (2.3%)
Time since last birth (years) 44 3.7 (2.4, 7.0) 44 3.7 (2.4, 7.0) N/A N/A
Age at first birth (years) 44 29 (26, 32) 44 29 (26, 32) N/A N/A
History of breastfeeding 44 37 (84.1%) 44 37 (84.1%) N/A N/A
 Total months breastfeeding 37 12 (6, 19) 37 12 (6, 19) N/A N/A
Total months breastfeeding (with no breastfeeding considered to be 0 months) 44 7 (3, 18) 44 7 (3, 18) N/A N/A
Relative with breast/ovarian cancer 298 150 (50.3%) 41 26 (63.4%) 257 124 (48.2%)
Estrogen 174 36 (10, 61) 22 54 (45, 64) 152 30 (9, 60)
Progesterone 176 0.40 (0.20, 0.70) 22 0.25 (0.20, 0.40) 154 0.40 (0.20, 0.70)
Prolactin 176 7.95 (6.10, 10.45) 22 7.05 (5.80, 10.40) 154 8.10 (6.20, 10.50)
SHBG 149 91 (47, 167) 20 80 (38, 115) 129 93 (52, 191)
Testosterone 172 16 (11, 27) 21 11 (7, 20) 151 17 (12, 29)
IGF-1 205 173 (135, 222) 37 150 (126, 180) 168 182 (140, 230)
IGF-1/IGFBP-3 molar ratio 205 0.12 (0.10, 0.16) 37 0.12 (0.10, 0.14) 168 0.13 (0.10, 0.16)

The sample median (Q1, Q3) is given for continuous variables.