Table 1:
Subject characteristics, hormone measures, and IGF-1/IGFBP-3 molar ratio
Variable | N | All women (N=316) | N | Parous women (N=44) | N | Nulliparous women (N=272) |
---|---|---|---|---|---|---|
Age at donation (years) | 316 | 25 (21, 33) | 44 | 35 (32, 40) | 272 | 23 (21, 30) |
Ethnicity (Hispanic/Latino) | 315 | 9 (2.9%) | 44 | 1 (2.3%) | 271 | 8 (3.0%) |
Race | 316 | 44 | 272 | |||
Caucasian | 282 (89.2%) | 37 (84.1%) | 245 (90.1%) | |||
African American | 34 (10.8%) | 7 (15.9%) | 27 (9.9%) | |||
BMI | 316 | 24.9 (22.0, 29.7) | 44 | 27.4 (22.7, 33.3) | 272 | 24.5 (22.0, 29.1) |
Percent fat | 316 | 60 (40, 90) | 44 | 70 (50, 90) | 272 | 60 (40, 80) |
Current smoking | 316 | 13 (4.1%) | 44 | 0 (0.0%) | 272 | 13 (4.8%) |
Current drinking | 315 | 233 (74.0%) | 44 | 30 (68.2%) | 271 | 203 (74.9%) |
Age at first period (years) | 316 | 12.5 (12, 13) | 44 | 13 (12, 13) | 272 | 12 (12, 13) |
Number of live births | 44 | 44 | N/A | N/A | ||
1 | 17 (38.6%) | 17 (38.6%) | ||||
2 | 19 (43.2%) | 19 (43.2%) | ||||
3 | 7 (15.9%) | 7 (15.9%) | ||||
4 | 0 (0.0%) | 0 (0.0%) | ||||
5 | 1 (2.3%) | 1 (2.3%) | ||||
Time since last birth (years) | 44 | 3.7 (2.4, 7.0) | 44 | 3.7 (2.4, 7.0) | N/A | N/A |
Age at first birth (years) | 44 | 29 (26, 32) | 44 | 29 (26, 32) | N/A | N/A |
History of breastfeeding | 44 | 37 (84.1%) | 44 | 37 (84.1%) | N/A | N/A |
Total months breastfeeding | 37 | 12 (6, 19) | 37 | 12 (6, 19) | N/A | N/A |
Total months breastfeeding (with no breastfeeding considered to be 0 months) | 44 | 7 (3, 18) | 44 | 7 (3, 18) | N/A | N/A |
Relative with breast/ovarian cancer | 298 | 150 (50.3%) | 41 | 26 (63.4%) | 257 | 124 (48.2%) |
Estrogen | 174 | 36 (10, 61) | 22 | 54 (45, 64) | 152 | 30 (9, 60) |
Progesterone | 176 | 0.40 (0.20, 0.70) | 22 | 0.25 (0.20, 0.40) | 154 | 0.40 (0.20, 0.70) |
Prolactin | 176 | 7.95 (6.10, 10.45) | 22 | 7.05 (5.80, 10.40) | 154 | 8.10 (6.20, 10.50) |
SHBG | 149 | 91 (47, 167) | 20 | 80 (38, 115) | 129 | 93 (52, 191) |
Testosterone | 172 | 16 (11, 27) | 21 | 11 (7, 20) | 151 | 17 (12, 29) |
IGF-1 | 205 | 173 (135, 222) | 37 | 150 (126, 180) | 168 | 182 (140, 230) |
IGF-1/IGFBP-3 molar ratio | 205 | 0.12 (0.10, 0.16) | 37 | 0.12 (0.10, 0.14) | 168 | 0.13 (0.10, 0.16) |
The sample median (Q1, Q3) is given for continuous variables.