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. 2022 Jul 14;77(2):558–572. doi: 10.1002/hep.32620

FIGURE 5.

FIGURE 5

Plasma triggering receptor expressed on myeloid cells 2 (TREM2) levels are strongly associated with NAFLD progression. Distribution of subjects according to NASH Clinical Research Network histologic scoring system for (A) steatosis, (B) hepatocellular ballooning, and (C) lobular inflammation. Correlation between plasma TREM2 levels and plasma aspartate aminotransferase (AST) levels (D), and FibroScan‐AST score (E) in patients with biopsy‐proven NAFLD. (F) Logistic regression analysis for the prediction of NASH in the validation cohort (n = 170) patients with biopsy‐proven NAFLD. ALT, alanine aminotransferase; BMI, body mass index; HbA1c, hemoglobin A1c; OR, odds ratio.