Table 1.

Measurements of oxidative stress and inflammatory parameters.

	Control group	DN group	DN + ZnO-NPs group
HIF-1α (ng/ml)	0.36 ± 0.06	2.13 ± 0.2##a	0.66 ± 0.08##b
COX-2 (U/ml)	7.52 ± 0.51	35.42 ± 1.3##a	12.36 ± 0.77#a, ##b
NF-κB (pg/mg protein)	0.14 ± 0.03	1.08 ± 0.11##a	0.23 ± 0.04##b

HIF-1α, hypoxia inducible factor-1 alpha; COX-2, cyclooxygenase-2; NF-κB, nuclear factor kappa beta. Values are displayed as mean ± standard error (X ± SE); ^a: P compared to control group; ^b: P compared to DN group; ^#: P< 0.05; ^##: P< 0.001; n = 10.