Table 3.
Serum lipid profile among studied groups.
| Parameters | Control (n = 15) | PCOS-IR (n = 12) | MET (n = 12) | SeNPs (n = 12) | SeNPs + MET (n = 12) |
|---|---|---|---|---|---|
| TG (mg/dL) | 61.68 ± 6.18 | 107.37 ± 4.47a,c,d,e | 87.12 ± 2.92a,b,e | 83.72 ± 6.81a,b | 64.11 ± 3.82b,c |
| TC (mg/dL) | 83.55 ± 5.21 | 134.89 ± 6.43a,c,d,e | 98.52 ± 2.67a,b | 102.64 ± 4.22a,b | 96.45 ± 3.51a,b |
| HDL-C (mg/dL) | 52.61 ± 6.37 | 23.14 ± 3.45a,c,d,e | 42.53 ± 5.16a,b | 39.33 ± 5.71a,b | 48.61 ± 3.08a,b |
| LDL-C (mg/dL) | 22.31 ± 4.52 | 90.43 ± 2.54a,c,d,e | 39.23 ± 2.85a,b | 47.37 ± 4.24a,b | 35.25 ± 2.79a,b |
Data were expressed as mean ± SD, aSignificant change vs. control, bSignificant change vs. PCOS-IR, cSignificant change vs. MET, dSignificant change vs. SeNPs, eSignificant change vs SeNPs + MET. PCOS, Polycystic ovarian syndrome; MET, Metformin; SeNPs, Selenium nanoparticles. IR, insulin Resistance; TG, triacylglycerol; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.