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. 2022 Dec 23;14(2):1011–1023. doi: 10.1039/d2fo02846h

Beta-coefficients (95% CIs) for specific transformed urine flavonoid metabolites (independent variable) and transformed liver markers (dependent variable) in individuals diagnosed with MetS by using a linear regression model.

  ALT   AST     GGT
Transformed urinary metabolites B coefficient 95% CI p-Value FDR-adjusted p-value B coefficient 95% CI p-Value FDR-adjusted p-value B coefficient 95% CI p-Value FDR-adjusted p-value
Flavanol
3′-ME-EC −0.01 (−0.14, 0.11) 0.819 0.967 0.003 (−0.13, 0.13) 0.969 0.969 −0.02 (−0.14, 0.11) 0.785 0.967
Flavanones
Naringenin 4′-GlcUA −0.03 (−0.15, 0.09) 0.662 0.927 −0.01 (−0.13, 0.12) 0.914 0.936 −0.15 (−0.26, −0.03) 0.014 0.327
Naringenin 7′-GlcUA −0.04 (−0.16, 0.08) 0.549 0.915 0.02 (−0.10, 0.14) 0.746 0.922 −0.12 (−0.24, −0.01) 0.038 0.329
Hesperetin 3′-GlcUA −0.08 (−0.20, 0.04) 0.184 0.627 −0.03 (−0.16, 0.09) 0.593 0.899 −0.12 (−0.24, −0.002) 0.047 0.329
Flavonols
Kaempferol-3-GlcUA −0.07 (−0.18, 0.05) 0.270 0.727 −0.05 (−0.17, 0.07) 0.413 0.899 −0.04 (−0.15, 0.08) 0.522 0.914
Myricetin 0.005 (−0.12, 0.13) 0.939 0.967 −0.04 (−0.16, 0.08) 0.517 0.899 −0.01 (−0.13, 0.11) 0.890 0.967
Isorhamnetin −0.01 (−0.14, 0.12) 0.908 0.967 0.01 (−0.12, 0.14) 0.880 0.936 0.03 (−0.09, 0.16) 0.629 0.927