Beta-coefficients (95% CIs) for specific transformed urine flavonoid metabolites (independent variable) and transformed liver markers (dependent variable) in individuals diagnosed with MetS by using a linear regression model.
ALT | AST | GGT | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Transformed urinary metabolites | B coefficient | 95% CI | p-Value | FDR-adjusted p-value | B coefficient | 95% CI | p-Value | FDR-adjusted p-value | B coefficient | 95% CI | p-Value | FDR-adjusted p-value |
Flavanol | ||||||||||||
3′-ME-EC | −0.01 | (−0.14, 0.11) | 0.819 | 0.967 | 0.003 | (−0.13, 0.13) | 0.969 | 0.969 | −0.02 | (−0.14, 0.11) | 0.785 | 0.967 |
Flavanones | ||||||||||||
Naringenin 4′-GlcUA | −0.03 | (−0.15, 0.09) | 0.662 | 0.927 | −0.01 | (−0.13, 0.12) | 0.914 | 0.936 | −0.15 | (−0.26, −0.03) | 0.014 | 0.327 |
Naringenin 7′-GlcUA | −0.04 | (−0.16, 0.08) | 0.549 | 0.915 | 0.02 | (−0.10, 0.14) | 0.746 | 0.922 | −0.12 | (−0.24, −0.01) | 0.038 | 0.329 |
Hesperetin 3′-GlcUA | −0.08 | (−0.20, 0.04) | 0.184 | 0.627 | −0.03 | (−0.16, 0.09) | 0.593 | 0.899 | −0.12 | (−0.24, −0.002) | 0.047 | 0.329 |
Flavonols | ||||||||||||
Kaempferol-3-GlcUA | −0.07 | (−0.18, 0.05) | 0.270 | 0.727 | −0.05 | (−0.17, 0.07) | 0.413 | 0.899 | −0.04 | (−0.15, 0.08) | 0.522 | 0.914 |
Myricetin | 0.005 | (−0.12, 0.13) | 0.939 | 0.967 | −0.04 | (−0.16, 0.08) | 0.517 | 0.899 | −0.01 | (−0.13, 0.11) | 0.890 | 0.967 |
Isorhamnetin | −0.01 | (−0.14, 0.12) | 0.908 | 0.967 | 0.01 | (−0.12, 0.14) | 0.880 | 0.936 | 0.03 | (−0.09, 0.16) | 0.629 | 0.927 |