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. 2023 Jan 10;8(1):e165207. doi: 10.1172/jci.insight.165207

Figure 3. C-10 ameliorates albuminuria and glomerulosclerosis in mice with ADRN.

Figure 3

(A) Urinary albumin/creatinine ratio (UACR) in control or ADRN mice treated with vehicle or C-10. (B) Twelve-hour urinary albumin excretion (UAE) in control and ADRN mice. (C) Periodic acid–Schiff–stained kidney images at ×200 (top) and ×400 (bottom) magnifications. Scale bars: 50 μm. (D) Glomerulosclerosis scoring in control and ADRN mice. (n = 6 mice per group). ***P < 0.001, ****P < 0.0001 compared with control group; #P < 0.05, ##P < 0.01, ####P < 0.0001 compared with ADR+Vehicle mice by 1-way ANOVA with Bonferroni’s correction.