FIG 2.

CAR T-cell persistence over time by response at data cutoff in patients who had evaluable samples: (A) peak CAR T-cell expansion and AUC (horizontal lines represent the median and interquartile range); (B) frequency of patients with ongoing response, relapse, or no response, by CAR presence (CAR T+), MRD negativity (MRD–), and MRD positivity (MRD+); and (C) ROC curves of true-positive (sensitivity) versus false-positive (specificity) rates for MRD predictability at months 1, 3, and 6 of relapse and nonresponse. AUC, area under the curve; CAR, chimeric antigen receptor; MRD, minimal residual disease; ROC, receiver operating characteristic.