Table 1. Diagnostic accuracy of L3-CTAB and L3-SSE from infective larvae of S. venezuelensis .
Diagnostic parameters | L3-CTAB | L3-SSE | ||||
---|---|---|---|---|---|---|
|
|
|||||
Cut-off | 1 | 2 | 3 | 1 | 2 | 3 |
OD (450 nm) | 0.214 | 0.286 | 0.589 | 0.083 | 0.365 | 0.458 |
% Sensitivity | 100 | 95 | 70 | 100 | 92.5 | 77.5 |
% Specificity | 90.11 | 97.8 | 100 | 15.38 | 94.51 | 100 |
Likelihood ratio | 10.11 | 43.22 | ∞ | 1.18 | 16.83 | ∞ |
% Positive predictive value | 81.63 | 95 | 100 | 34.19 | 88.10 | 100 |
% Negative predictive value | 100 | 97.8 | 88.35 | 100 | 96.63 | 91 |
Diagnostic accuracy | 0.93 | 0.97 | 0.91 | 0.41 | 0.94 | 0.93 |
% Cross-reactivity | 11.63 | 2.33 | 0 | 79.07 | 9.30 | 0 |
L3-CTAB = Surface cuticle antigens from infective larvae of S. venezuelensis extracted with CTAB detergent; L3-SSE = Soluble somatic extract from infective larvae of S. venezuelensis; ∞ = undefined.