Fig. 1: temporal substitution of the Gamma variant of concern (VOC) for the Delta VOC from July to December 2021 in municipalities of the state of Rondônia. A) July: absence of Delta VOC detection; B) August-September: insertion of the Delta VOC followed by reduction of the Gamma VOC; C) October-November: increase in the Delta VOC, indicating the overlap profile in relation to the Gamma VOC; D) December: only Delta VOC was detected. Brazilian states: Acre (AC), Amazonas (AM), Pará (PA), Mato Grosso (MT).