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Genomic analysis in the MSI-H altered and wt groups. (A) Distribution of the variant types in the MSI-H altered and wt groups; (B) Number of variants per sample in MSI-H altered and wt groups. (C) Top 10 frequently mutated genes in tumors from MSI-H altered (left) and wt (right). (D) Mutation frequency of several CRC-related key genes in MSI-H altered and wt groups, respectively.
