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. 2023 Jan 9;13:974793. doi: 10.3389/fimmu.2022.974793

Figure 4.

Figure 4

Somatic variant features of tumor from MSI-H altered and wt groups (A) Distribution and types of somatic variants in MSI-H altered and wt groups. (B) Distribution and types of genetic variants in patients with Lynch syndrome. (C) Comparison of MLH1 methylation levels among the MSS wt, MSS BRAF V600E, MSS Her2 amplification, MSS fusion, MSI-H wt, MSI-H BRAFV600E , MSI-H fusion groups. (D, E) The TMB and TNB scores of CRC patients in the MSI-H altered and wt subgroups. The analyzed data of (C) was obtained from The Cancer Genome Atlas (TCGA) database.