Table 2.

Metabolites with Spearman’s rank correlation coefficient |ρ| > 0.4 with MELD score

Compound Name	ρ	Compound Name	ρ
7,9-Dimethylguanine	0.71	N-Phenylacetylglutamine	−0.57
β-d-Glucopyranuronic acid	0.65	Lysylvaline	0.55
Saccharopine	0.60	Glucosylgalactosyl hydroxylysine	0.55
Ureidoisobutyric acid	−0.58	Citramalic acid	0.55
3,7-Dimethyluric acid	−0.57	Hydantoin-5-propionic acid	0.54
m1I	0.57	Paraxanthine	−0.54
4-Acetamidobutanoic acid	0.56	Cystathionine	0.53
3-Hydroxyanthranilic acid	0.55	Ethanolamine	0.51
1,3,7-Trimethyluric acid	−0.40	l-Pyroglutamic acid	−0.49
3-Indoxyl sulfate	−0.51	m2,2G	0.48
N3,N4-Dimethyl-l-arginine	0.40	n-Ribosylhistidine	0.48
3-Methylcrotonylglycine	0.48	m3C /m5C	−0.48
Benzoic acid	−0.48	Acetoacetic acid	0.40
Sucrose	0.47	Tyr-lys	−0.47
m1A	0.47	Hypaphorine	−0.47
Am	0.47	p-Cresylsulfate	−0.46
Acetoacetic acid	0.40	DHU	0.45
3-Hydroxysuberic acid	0.45	N6-Acetyl-l-lysine	0.45
4-Hydroxy-3-methoxyphenylglycol sulfate	0.45	Leucine	0.45
Anserine	0.44	Hypoxanthine	−0.45
But-1-ene-1,2,4-tricarboxylic acid	0.40	Cytosine	0.40
1,7-Dimethyluric acid	−0.43	Creatinine	0.44
3-Methyluric acid	−0.42	5-Aminovaleric acid	0.41
1-(β-d-Ribofuranosyl)-1,4-dihydronicotinamide	0.41	N-Acetyl-d-galactosamine 4-sulfate	0.42

DHU, dihydrouridine; ρ, Spearman’s rank correlation coefficient; m¹I, N1-methylinosine; m¹A, N1-methyladenosine; Am, 2′-O-methyladenosine; m^2,2G, N2,N2-dimethylguanosine; m³C/m⁵C, 3-methylcytidine/5-methylcytidine, these two nucleosides co-eluted in 2DLC-MS.