Table 2.
Change in Fatty Acid Composition (%) After Two-Weeks of Atorvastatin or No-Treatment.
|
Table 2A Fatty acid |
No Treatment (n = 10) Baseline |
Follow-up | p-value |
|---|---|---|---|
| 12:0 | 0.24 ± 0.24 | 0.21 ± 0.23 | 0.11 |
| 14:0 | 0.93 ± 0.34 | 0.70 ± 0.24 | 0.02 |
| 14:1 | 0.17 ± 0.11 | 0.14 ± 0.13 | 0.11 |
| 16:0 | 21.86 ± 1.97 | 21.33 ± 1.28 | 0.49 |
| 16:1 | 1.63 ± 0.36 | 1.39 ± 0.27 | 0.06 |
| 18:0 | 7.64 ± 1.34 | 7.65 ± 1.12 | 0.99 |
| 18:1n-9 | 18.11±2.17 | 18.05 ± 2.11 | 0.9 |
| 18:1n-7 | 1.33 ± 0.33 | 1.35 ± 0.25 | 0.85 |
| 18:2n-6 (LA) | 33.51 ± 4.52 | 35.15 ± 5.08 | 0.26 |
| 18:3n-6 | 0.46 ± 0.18 | 0.4 ± 0.16 | 0.42 |
| 18:3n-3 | 0.61 ± 0.2 | 0.56 ± 0.24 | 0.46 |
| 20:0 | 0.2 ± 0.05 | 0.18 ± 0.04 | 0.41 |
| 20:1 | 0.12 ± 0.03 | 0.11 ± 0.03 | 0.35 |
| 20:2n-6 | 0.14 ± 0.04 | 0.18 ± 0.11 | 0.19 |
| 20:3n-6 | 1.36 ± 0.49 | 1.33 ± 0.48 | 0.79 |
| 20:4n-6 (AA) | 7.88 ± 1.07 | 7.77±2.17 | 0.85 |
| 20:5n-3 | 1.27 ± 2.03 | 0.46 ± 0.17 | 0.24 |
| 22:4n-6 | 0.17 ± 0.05 | 0.16 ± 0.05 | 0.57 |
| 24:0 | 0.16 ± 0.06 | 0.14 ± 0.05 | 0.32 |
| 22:5n-3 | 0.48 ± 0.19 | 0.46±0.17 | 0.62 |
| 22:6n-3 | 1.6 ± 1.07 | 1.6 ± 1.11 | 0.99 |
|
Table 2B Fatty acid |
Statin (n = 20) Baseline |
Follow-up | p-value |
|
| |||
| 12:0 | 0.27 ± 0.22 | 0.37 ± 0.3 | 0.03 |
| 14:0 | 0.88 ± 0.43 | 0.84 ± 0.5 | 0.69 |
| 14:1 | 0.17 ± 0.14 | 0.21 ± 0.18 | 0.06 |
| 16:0 | 22.29 ± 2.38 | 21.83 ± 2.27 | 0.35 |
| 16:1 | 1.64 ± 0.84 | 1.71 ± 1.00 | 0.59 |
| 18:0 | 8.07 ± 1.16 | 8.31 ± 1.32 | 0.11 |
| 18:1n-9 | 18.50 ± 2.48 | 20.56 ± 5.08 | 0.06 |
| 18:1n-7 | 1.39 ± 0.36 | 1.63 ± 0.35 | 0.001 |
| 18:2n-6 (LA) | 33.31 ± 4.84 | 29.76 ± 4.15 | 0.002 |
| 18:3n-6 | 0.45 ± 0.24 | 0.45 ± 0.16 | 0.95 |
| 18:3n-3 | 0.62 ± 0.19 | 0.63 ± 0.37 | 0.84 |
| 20:0 | 0.18± 0.06 | 0.19 ± 0.09 | 0.35 |
| 20:1 | 0.14 ± 0.04 | 0.18 ± 0.09 | 0.03 |
| 20:2n-6 | 0.18 ± 0.05 | 0.18 ± 0.04 | 0.59 |
| 20:3n-6 | 1.29 ± 0.25 | 1.26 ± 0.25 | 0.54 |
| 20:4n-6 (AA) | 7.73 ± 1.38 | 8.99 ± 2.10 | 0.007 |
| 20:5n-3 | 0.60 ± 0.35 | 0.62 ± 0.28 | 0.88 |
| 22:4n-6 | 0.18 ± 0.04 | 0.19 ± 0.04 | 0.2 |
| 24:0 | 0.19 ± 0.13 | 0.16 ± 0.09 | 0.13 |
| 22:5n-3 | 0.43 ± 0.08 | 0.42 ± 0.09 | 0.84 |
| 22:6n-3 | 1.48 ± 0.53 | 1.49 ± 0.58 | 0.84 |
Data are mean ± SD with fatty acid composition as a percent of the whole. AA; arachidonic acid. LA; Linoleic acid.