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. Author manuscript; available in PMC: 2023 Jan 23.
Published in final edited form as: Bioconjug Chem. 2022 Mar 18;33(4):544–554. doi: 10.1021/acs.bioconjchem.2c00057

Figure 4.

Figure 4.

(a) Fluorescence micrographs of HCT116 colorectal cancer cells showing high colocalization of LysoTracker Green DND-26 (left) with HEX(NAG) substrate 6 (middle) and the merged images (right). (Reprinted (adapted) with permission.71 Copyright (2019) American Chemical Society). (b) Dynamic change in fluorescence images of chloroquine-treated HeLa cervical cancer cells stained with fluorescent HEX(NAG) substrate 7. Reproduced with permission from Chem. Pharm. Bull. 68. 526–533. Copyright 2021,The Pharmaceutical Society of Japan.9 (c) White light and fluorescence images of a surgical specimen from a colorectal cancer patient at 20 minutes after application of fluorescent HEX(NAG) substrate 8. (Reprinted (adapted) with permission.74 Copyright (2016) American Chemical Society)