Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 12;7(1):24–37. doi: 10.1038/s41551-022-00969-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — a, Treatment schedule of the ovarian cancer peritoneal dissemination xenograft model. NSG mice were injected intraperitoneally with 5 × 10⁵ KOC7c cells expressing luciferase. From the third day after the ovarian cancer inoculation, 1 × 10⁶ iCAR-T_CTL, DGK-dKO-iCAR-T_CTL, iCAR-T_CTL-mbIL15tg, DGK-dKO-iCAR-T_CTL-mbIL15tg, pCAR-T_CTL or DGK-pKO-pCAR-T_CTL-mbIL15tg were injected intraperitoneally (n = 5 for each group). b, In vivo bioluminescence imaging of Renilla luciferase-labelled KOC7c. c, Survival of treated mice at the indicated timepoints after the injection. log-rank test with Bonferroni multiple comparisons test. d, In vivo bioluminescence imaging of firefly luciferase-labelled injected CAR-T cells in NSG mice. e, Total flux (photons s⁻¹) of injected CAR-T cells at the indicated timepoints. One-way ANOVA with Tukey’s multiple comparisons test.