Table 2.
Changes in auxological parameter after GnRHa treatment or GnRHa + GH combination treatment.
| Variable | GnRHa (n = 188) | GnRHa + GH (n = 22) | P-value |
|---|---|---|---|
| 1 year after treatment | |||
| Height(cm) | 138.84 ± 5.00 | 136.29 ± 4.27 | 0.023 |
| Height SDS | 1.06 ± 0.72 | 0.60 ± 0.83 | 0.006 |
| PAH (cm) | 158.76 ± 5.29 | 154.52 ± 4.73 | < 0.001 |
| PAH SDS | −0.42 ± 1.06 | −1.29 ± 0.99 | < 0.001 |
| At end of treatment | |||
| Height (cm) | 149.28 ± 5.02 | 147.89 ± 4.83 | 0.346 |
| Height SDS | 0.50 ± 0.77 | 0.37 ± 0.73 | 0.278 |
| PAH (cm) | 166.25 ± 5.26 | 164.07 ± 4.99 | 0.067 |
| PAH SDS | 1.04 ± 1.00 | 0.63 ± 0.95 | 0.068 |
| At final adult height | |||
| FAH (cm) | 161.07 ± 4.78 | 159.63 ± 3.86 | 0.174 |
| Height SDS | −0.09 ± 0.94 | −0.23 ± 0.77 | 0.530 |
GnRHa Gonadotropin-releasing hormone agonist, GH Growth hormone, CA Chronological age, BA Bone age, SDS Standard deviation score, BMI Body mass index, PAH Predicted adult height-calculated with advanced table of baley–Pinneau (BP) method, FAH Final adult height.