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. 2023 Jan 23;6:93. doi: 10.1038/s42003-023-04471-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, b. tSNE plots of all organisms within the analyzed database, colored either by phylum (a) or while highlighting classes within Chordata (b). Dotted frame—Chordates in (a), birds in (b). c, d Ratio between observed and expected genome architecture (AR rates) within each class, either with (c) or without (d) mt-tRNA genes. The vertical dashed line and grey rectangle show 1:1 ratio (indicating no difference) and ±0.25 interval around it, respectively. The expected AR-rate distribution was calculated by random sampling of 21 organisms from each class followed by label shuffling 10,000 times. The observed distribution was generated by a similar process but without shuffling. See also Supplementary Data S5 and S6 for raw data (https://figshare.com/projects/Shtolz_2022_mtDNA_evolutionary_rearrangements/156008).