Table 1.
Demographics and clinical characteristics
| Variables | Early-onset n = 67 |
Typical-onset n = 195 |
Late-onset n = 94 |
Statistic | P |
|---|---|---|---|---|---|
| Mean(SD) | Mean( SD) | Mean (SD) | |||
| Age, year | 17.4 (1.2) | 25.8 (5.8) | 43.1 (2.9) | F = 703.63 | < 0.001 |
| Female, n (%) | 31 (46.3%) | 91 (46.7%) | 52 (55.3%) | χ2 = 2.12 | 0.346 |
| Education, year | 10.0 (2.3) | 10.0 (3.1) | 10.4 (3.2) | F = 0.57 | 0.568 |
| Age of onset, year | 16.3 (1.0) | 24.9 (5.7) | 42.7 (2.9) | F = 788.34 | < 0.001 |
| Duration of illness, month | 15.3 (9.0) | 14.3 (10.8) | 8.3 (3.1) | F = 16.94 | < 0.001 |
| PANSS | |||||
| Positive | 23.6 (5.7) | 24.6 (4.9) | 23.6 (4.1) | F = 1.75 | 0.176 |
| Negative | 20.8 (7.5) | 19.9 (6.3) | 19.1 (6.2) | F = 1.39 | 0.250 |
| General psychopathology | 40.9 (8.2) | 39.9 (7.7) | 36.5 (6.2) | F = 8.90 | < 0.001 |
| MCCB | |||||
| Speed of processing | 42.3 (9.4) | 41.1 (10.2) | 43.7 (8.8) | F = 2.27 | 0.105 |
| Verbal learning | 44.7 (10.9) | 40.5 (14.1) | 45.5 (12.9) | F = 5.58 | 0.004 |
| Working memory | 41.7 (11.1) | 40.3 (11.8) | 44.8 (10.6) | F = 4.99 | 0.007 |
| Reasoning and problem solving | 43.4 (11.3) | 41.6 (12.5) | 44.5 (11.6) | F = 2.02 | 0.134 |
| Visual learning | 43.0 (11.1) | 39.6 (11.1) | 43.2 (10.4) | F = 4.54 | 0.011 |
| Social cognition | 46.6 (8.9) | 45.3 (10.6) | 47.6 (10.4) | F = 1.66 | 0.193 |
| Attention/vigilance | 39.2 (8.8) | 38.3 (9.7) | 40.4 (8.8) | F = 1.66 | 0.192 |
PANSS Positive and Negative Syndrome Scale for Schizophrenia—30 items; MCCB the MATRICS Consensus Cognitive Battery