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. 2023 Jan 10;13:1091018. doi: 10.3389/fphar.2022.1091018

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Copyright © 2023 Zhou and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Construction of molecular subtypes in lung adenocarcinoma. (A) The heatmap was utilized to present the transcriptome pattern of 152 wtn signal pathway related genes in distinct samples. (B,C) Unsupervised clustering was conducted to divided samples into four subgroups performed according to the 152 wtn signal pathway related genes patterns. (D) Kaplan–Meier survival model for lung adenocarcinoma, p < 0.001. (E) The heatmap was utilized to present the transcriptome pattern of 152 wtn signal pathway related genes in distinct subtypes. Red/blue represented high/low expression of genes. The comments on the right include TNM stage, clinical grade/stage, gender, age, project and cluster, respectively.