Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 10;13:1066713. doi: 10.3389/fphar.2022.1066713

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Wan, Wu, Li and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Sevoflurane upregulated p-tau in the fetal brains via the CB1R/CDK5/p25 pathway. Assays of western blotting (n = 3) demonstrating the expression of CB1R, CDK5, p35, p25, tau, and p-tau (A,B) and the value of p25/p35 (C) and p-tau/tau (D). Immunofluorescence double staining of CB1R and Nestin (E, n = 3) and CDK5 and Nestin (F, n = 3) in the fetal rat brains. Quantification of CB1R/Nestin-positive cells (G) and CDK5/Nestin-positive cells (H). Data are manifested as mean ± S.E.M. *p < .05, **p < .01, vs. the Con + Veh group; #p < .05, ##p < .01, vs. the Sevo + Veh group.