TABLE 4.
Adverse reactions and cases between the two groups.
| Outcomes | Trials | Experimental group (events/total | Control group (events/total | Statistical method | RR, 95%Cl | I2 | P |
|---|---|---|---|---|---|---|---|
| Erythra | 3 | 2/167 | 4/166 | REM | 0.55 [0.11–2.60] | 0 | 0.45 |
| Headache | 3 | 2/145 | 2/144 | REM | 0.99 [0.20–5.00] | 0 | 0.99 |
| Arrhythmia | 3 | 0/92 | 3/92 | REM | 0.32 [0.05–2.09] | 0 | 0.24 |
| Dizziness | 3 | 4/102 | 17/102 | REM | 0.24 [0.08–0.67] | 0 | 0.007 |
| Vomiting | 2 | 5/92 | 10/92 | REM | 0.47 [0.15–1.44] | 0 | 0.19 |
| Nauseating | 2 | 5/104 | 10/104 | REM | 0.47 [0.16–1.44] | 0 | 0.19 |
| Red face | 1 | 1/20 | 0/20 | - | - | - | - |
| Chest tightness | 1 | 0/55 | 1/55 | - | - | - | - |
| Chill | 1 | 1/78 | 0/79 | - | - | - | - |
| Liver dysfunction | 3 | 2/167 | 4/166 | REM | 0.55 [0.11–2.60] | 0 | 0.45 |
| Renal dysfunction | 3 | 8/170 | 8/170 | REM | 1 [0.37–2.73] | 0 | 1 |
| Hypokalaemia | 2 | 2/56 | 0/56 | REM | 3.12 [0.31–30.98] | 0 | 0.33 |
| Low blood pressure | 3 | 1/109 | 4/108 | REM | 0.39 [0.07–2.03] | 0 | 0.26 |