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The relationship between TLS gene signature and existing markers of immunotherapy. (A) The landscape of genetic variation of the TLS gene signature in the OV cohort. (B) The CNV variation frequency of the TLS gene signature in the OV cohort. The proportion (C) and frequency (D) of tumor mutation load between high and low TLS gene signature groups. (E) The distinction of PD-L1 and CTLA-4 between high and low TLS gene signature groups. (∗p < .05, ∗∗p < .01, and ∗∗∗p < .001).
