TABLE 2.
References | Study design | Intervention type | Stimulation parameters | The total duration of treatment | Follow up | ||||
Frequency | Intensity | Coil type | Sites | No. of plus | |||||
Benninger et al. (2011) | Parallel | rTMS | 50 Hz | 80%AMT | C | M1 + DLPFC | 8,000 | 2 weeks | Yes (1 month) |
Chang et al. (2016) | Crossover | rTMS | 10 Hz | 90%RMT | C | M1-LL | 1,000 | 5 days | Yes (12 days) |
Chen et al. (2014) | Parallel | rTMS | 1, 5 Hz | 100%RMT | F8 | M1 | 1,600 | 10 days | Yes (1 month) |
Chen and Li (2021) | Parallel | rTMS + Levodopa and Benserazide Hydrochlo-ride | 1 Hz | 60%AMT | F8 | FRL | NR | 2 months | No |
Benninger et al. (2012) | Parallel | rTMS | 50 Hz | 80%AMT | NR | M1 | 4,800 | 2 weeks | Yes (1 month) |
Guo (2021) | Parallel | rTMS + Pramipexole | 0.5 Hz | 90%RMT | C | M1 | 3,200 | 4 weeks | No |
Huang et al. (2021) | Parallel | rTMS + Rehabilitation Training | 1, 5 Hz | 80%AMT | F8 | PFC | 800 | 1 month | No |
Kim et al. (2015) | Crossover | rTMS | 10 Hz | 90%RMT | C | M1-LL | 1,000 | 5 days | Yes (12 days) |
Li (2016) | Parallel | rTMS | 0.5, 5 Hz | 90∼100%AMT | NR | DLPFC | 750 | 4 weeks | No |
Li et al. (2022) | Parallel | rTMS + Pramipexole | 1, 5 Hz | 80%AMT | NR | PFC | NR | 3 months | No |
Maruo et al. (2013) | Crossover | rTMS | 10 Hz | 100%RMT | F8 | M1 | 3,000 | 3 days | No |
Ren and He (2022) | Parallel | rTMS | 10 Hz | 90%AMT | F8 | DLPFC | 800 | 4 weeks | No |
Tang et al. (2015) | Parallel | rTMS | 1 Hz | 120%RMT | F8 | M1 | 250 | 1 month | No |
Wang et al. (2019) | Parallel | rTMS | 5 Hz | 90%RMT | F8 | M1-LL | 900 | 3 weeks | Yes (1 month) |
Wu et al. (2019) | Parallel | rTMS + Rehabilitation Training | 1, 5 Hz | 80%AMT | C | DLPFC | 1,600 | 4 weeks | No |
Yang et al. (2013) | Parallel | rTMS + Treadmill training | 5 Hz | 100%RMT | F8 | M1-LL | 1,200 | 4 weeks | No |
Yu et al. (2017) | Parallel | rTMS | 5 Hz | 100%AMT | F8 | DLPFC | 800 | 10 days | Yes (1 month) |
Zhang et al. (2020) | Parallel | rTMS + Rehabilitation Training | 10 Hz | NR | F8 | DLPFC | 800 | 3 months | No |
rTMS, repetitive transcranial magnetic stimulation; M1, primary motor cortex; DLPFC, dorsolateral prefrontal cortex; AMT, active motor threshold; C, circular; RMT, resting motor threshold; F8, figure of 8; M1-LL, primary motor cortex of the lower leg; PFC, prefrontal cortex; FRL, frontal right lobe; NR, not reported.