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. 2022 Nov 27;10(1):673–684. doi: 10.1002/ehf2.14245

Table 2.

Comparison of clinical outcomes

Mode of death Non‐HFpEF (LVEF <50%) HFpEF (LVEF ≥50%)

Young

N = 575

Older

N = 1159

Very old

N = 319

P‐value

Young

N = 182

Older

N = 894

Very old

N = 429

P‐value
All‐cause death 60 (10.4) 308 (26.6) 117 (36.7) <0.001 10 (5.5) 187 (20.9) 136 (31.7) <0.001
CVD 39 (6.8) 198 (17.1) 65 (20.4) <0.001 5 (2.7) 77 (8.6) 52 (12.1) <0.001
HFD 18 (3.1) 104 (9.0) 44 (13.8) <0.001 2 (1.1) 40 (4.5) 29 (6.8) <0.001
SCD 15 (2.6) 75 (6.5) 15 (4.7) 0.001 3 (1.6) 23 (2.6) 14 (3.3) 0.55
Other‐CVD 6 (1.0) 19 (1.6) 6 (1.9) 0.52 0 14 (1.6) 9 (2.1) 0.14
Non‐CVD 21 (3.7) 110 (9.5) 52 (16.3) <0.001 5 (2.7) 110 (12.3) 84 (19.6) <0.001
Infection 2 (0.3) 28 (2.4) 13 (4.1) <0.001 2 (1.1) 27 (3.0) 19 (4.4) 0.09
Malignancy 3 (0.5) 26 (2.2) 12 (3.8) <0.001 0 27 (3.0) 13 (3.0) 0.03
Fatal bleeding 2 (0.3) 4 (0.3) 1 (0.3) >0.99 1 (0.5) 3 (0.3) 4 (0.9) 0.27
Digestive disease 0 2 (0.2) 2 (0.6) 0.14 1 (0.5) 4 (0.4) 3 (0.7) 0.78
Respiratory failure 1 (0.2) 9 (0.8) 0 0.14 0 13 (1.5) 4 (0.9) 0.27
Renal failure 0 3 (0.3) 2 (0.6) 0.17 0 3 (0.3) 7 (1.6) 0.02
Others 8 (1.4) 32 (2.8) 16 (5.0) <0.001 1 (0.5) 29 (3.2) 30 (7.0) <0.001
Unknown 5 (0.9) 6 (0.5) 6 (1.9) 0.06 0 4 (0.4) 4 (0.9) 0.38
HF readmission 96 (16.7) 345 (29.8) 319 (38.6) <0.001 33 (18.1) 232 (26.0) 135 (31.5) 0.002

CVD, cardiovascular death; HFD, heart failure death; SCD, sudden cardiac death.

Values are n (%).