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. 2022 Oct 20;10(1):416–431. doi: 10.1002/ehf2.14211

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© 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Functional enrichment analysis. (A) Gene Ontology (GO) function analysis results on common differentially expressed genes (DEGs). (B) Kyoto Encyclopaedia of Genes and Genomes (KEGG) function analysis results on common DEGs. (C) The co‐signalling pathways in heart failure with preserved ejection fraction (HFpEF) and non‐alcoholic fatty liver disease (NAFLD). (D) Signalling pathways found by Gene Set Enrichment Analysis (GSEA) in HFpEF. (E) Signalling pathways found by GSEA in non‐alcoholic fatty liver (NAFL). (F) Signalling pathways found by GSEA in non‐alcoholic steatohepatitis (NASH).