TABLE 3.
Variables | B | S.E. | Wald | p | Exp (B) | 95.0% CI for EXP (B) | ||
Lower | Upper | |||||||
All the subjects | Body mass index | 0.196 | 0.033 | 35.529 | 0 | 1.216 | 1.14 | 1.297 |
(n = 1,137)* | Serum homocysteine concentration (μmol/L) | 0.157 | 0.05 | 9.824 | 0.002 | 1.17 | 1.061 | 1.291 |
Serum folate concentration (mmol/L) | 0.018 | 0.01 | 3.548 | 0.06 | 1.018 | 0.999 | 1.038 | |
Constant | −7.796 | 0.899 | 75.15 | 0 | 0 | |||
MTHFR C677TCC | Body mass index | 0.182 | 0.054 | 11.408 | 0.001 | 1.2 | 1.079 | 1.333 |
Subgroup (n = 342)** | Serum homocysteine concentration (μmol/L) | 0.294 | 0.096 | 9.329 | 0.002 | 1.342 | 1.111 | 1.621 |
Serum folate concentration (mmol/L) | 0.041 | 0.018 | 5.536 | 0.019 | 1.042 | 1.007 | 1.079 | |
Constant | −9.053 | 1.628 | 30.928 | 0 | 0 | |||
MTHFR C677T CT | Body mass index | 0.164 | 0.052 | 9.771 | 0.002 | 1.178 | 1.063 | 1.306 |
Subgroup (n = 553)** | Serum homocysteine concentration (μmol/L) | 0.085 | 0.088 | 0.934 | 0.334 | 1.089 | 0.916 | 1.293 |
Serum folate concentration (mmol/L) | 0.02 | 0.015 | 1.761 | 0.185 | 1.02 | 0.991 | 1.05 | |
Constant | −6.833 | 1.328 | 26.485 | 0 | 0.001 | |||
MTHFR C677T TT | Body mass index | 0.174 | 0.072 | 5.906 | 0.015 | 1.19 | 1.034 | 1.369 |
Subgroup (n = 242)** | Serum homocysteine concentration (μmol/L) | 0.062 | 0.1 | 0.384 | 0.535 | 1.064 | 0.875 | 1.294 |
Serum folate concentration (mmol/L) | −0.014 | 0.021 | 0.458 | 0.499 | 0.986 | 0.947 | 1.027 | |
Constant | −5.491 | 1.975 | 7.729 | 0.005 | 0.004 |
*Establishment of prediction model for pregnancy induced hypertension.
**Internal validation of prediction model for pregnancy induced hypertension.