FIG. 2.

Inhibition of Cryptosporidium infection in cell lines transfected with inhibitors of host actin polymerization (Scar-WA [n = 297 transfected cells counted] and N-WASP-ΔA [n = 130]). Results are given as a percentage of the infection rate seen in untransfected cells in the same well. Control transfections include Scar-W (n = 242) and N-WASP (n = 325), which do not interfere with actin polymerization. Scar-WA (n = 178) and Scar-W (n = 184) expression does not inhibit T. gondii infection (which is independent of host cell actin), ruling out nonspecific inhibition of parasite invasion. Data are means of internal parasites ± standard deviations (error bars) for three separate experiments.