Table 3:
Mutation | Δ(H-Bond) | Δ(Salt Bridge) | Δ(SASA) (%) | ΔΔG(kcal/mol) |
---|---|---|---|---|
T158M | NC (2 lost, 2 new) |
NC | NC | 0.09 |
R133C | 3 lost | 1 lost | NC −10 |
0.29 |
R106W | 4 lost, 3 new | 2 lost | NC (buried) | −0.10 |
P152R | 1 lost, 3 new | NC 1 lost |
NC | 1.65 |
A140V | NC | NC | 11 NC |
−0.67 |
S134C | NC | NC | 22 NC |
1.32 |
R106Q | 4 lost, 3 new | 2 lost 3 lost |
NC | 0.13 |
D156E | NC | 1 lost, 1 new 2 lost |
11 NC |
0.92 |
R133H | 3 lost, 1 new | 1 lost NC |
NC −22 |
0.39 |
L100V | NC | NC | −10 NC |
1.28 |
F155S | NC (2 lost, 1 new) |
1 lost, 1 new 2 lost |
28 (buried) NC (buried) |
0.41 |
T158A | NC | NC 1 lost |
−11 −13 |
0.43 |
R111G | 3 lost, 1 new | 1 lost 2 lost |
NC | −0.54 |