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. 2023 Jan 10;10:1095143. doi: 10.3389/fped.2022.1095143

Table 2.

Response to IST with or without eltrombopag in children.

Group A Pediatric patients with IST + EPAG (n = 15) Group B Pediatric patients with IST only (n = 45) P
3 months Response n (%)
  Overall Response 8 (53.3) 21 (46.7) 0.655
  CR 3 (20.0) 2 (4.4) 0.094
  PR 5 (33.3) 19 (42.2)
  NR 7 (46.7) 22 (48.9)
  Off study 0 (0) 2 (4.4)
6 months Response n (%)
  Overall Response 10 (66.7) 26 (57.8) 0.543
  CR 7 (46.7) 6 (13.3) 0.012
  PR 3 (20.0) 20 (44.4)
  NR 5 (33.3) 14 (31.1)
  Off study 0 (0) 5 (11.1)
12 months Response n (%)
  Overall Response 10 (66.7) 32 (71.1) 0.754
  CR 8 (53.3) 12 (26.7) 0.058
  PR 2 (13.3) 20 (44.4)
  NR 3 (20.0) 6 (13.3)
  Off study 2 (13.3) 7 (15.6)

Note: EPAG, eltrombopag; IST, immunosuppressive therapy; CR, complete response; PR, partial response; NR, no response; OR, overall response.