Table 2.
Response to IST with or without eltrombopag in children.
| Group A Pediatric patients with IST + EPAG (n = 15) | Group B Pediatric patients with IST only (n = 45) | P | |
|---|---|---|---|
| 3 months Response n (%) | |||
| Overall Response | 8 (53.3) | 21 (46.7) | 0.655 |
| CR | 3 (20.0) | 2 (4.4) | 0.094 |
| PR | 5 (33.3) | 19 (42.2) | |
| NR | 7 (46.7) | 22 (48.9) | |
| Off study | 0 (0) | 2 (4.4) | |
| 6 months Response n (%) | |||
| Overall Response | 10 (66.7) | 26 (57.8) | 0.543 |
| CR | 7 (46.7) | 6 (13.3) | 0.012 |
| PR | 3 (20.0) | 20 (44.4) | |
| NR | 5 (33.3) | 14 (31.1) | |
| Off study | 0 (0) | 5 (11.1) | |
| 12 months Response n (%) | |||
| Overall Response | 10 (66.7) | 32 (71.1) | 0.754 |
| CR | 8 (53.3) | 12 (26.7) | 0.058 |
| PR | 2 (13.3) | 20 (44.4) | |
| NR | 3 (20.0) | 6 (13.3) | |
| Off study | 2 (13.3) | 7 (15.6) |
Note: EPAG, eltrombopag; IST, immunosuppressive therapy; CR, complete response; PR, partial response; NR, no response; OR, overall response.