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M. tuberculosis lacking Rv1625c has no fitness defect in a mouse model. (A and B) Bacterial burdens in the lungs (A) and spleens (B) of BALB/c mice infected with ~200 CFU of WT, ΔRv1625c, or complemented strain by the aerosol route. The data are from one experiment with five mice per group for each time point. The data are means ± the SD. **, P < 0.05 (ordinary one-way ANOVA with Dunnett’s multiple-comparison test).
