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. 2023 Jan 9;91(1):e00304-22. doi: 10.1128/iai.00304-22

FIG 2.

FIG 2

W-Hz inoculation decreases parasite liver load. (A and B) BALB/c WT mice were inoculated with 750 nmol of W-Hz i.v. and rested for 1 week or 1 month before receiving a 2,000-Pb-ANKA-Luc sporozoite i.v. injection. Parasite liver load was measured 42 h postinfection in photons per second (total flux). The nonparametric, unpaired Mann-Whitney test showed that there was a statistically significant difference between the naive control group and the group inoculated with W-Hz 1 week or 1 month before sporozoite infection. **, P ≤ 0.01;  n = 20. (C) Mice were inoculated with 250, 500, or 750 nmol of W-Hz i.v. and infected with 2,000 Pb-ANKA-Luc sporozoites 1 week later. Parasite liver load was measured 42 h postinfection in photons per second. The nonparametric, unpaired Mann-Whitney test gave a statistically significant difference between the naive control group and the groups inoculated with 500 or 750 nmol of W-Hz 1 week before sporozoite infection. The difference was higher in mice inoculated with 750 nmol of W-Hz. **, P ≤ 0.01; ns, P > 0.05; n  = 20. Error bars correspond to the standard error of the mean (SEM).