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. 2023 Jan 4;12:1089991. doi: 10.3389/fcimb.2022.1089991

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Copyright © 2023 Wu, Zhang, Chen, Xia, Zhu, Chen, Lin, Zheng, Hou, Li, Zhang, Chen and Hou

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Microbial species significantly changed after intervention and their correlation with clinical indicators. (A) The top 30 significantly changed species after FMT or FMT plus metformin and their correlation with clinical indicators based on samples from W0 and W4 of these two groups. (B) Significant corrections between HOMA-IR and significantly changed species with relative abundance greater than 0.001%, based on all samples from T2DM patients at W0 and W4 in metformin, FMT alone, and FMT plus metformin group. (C) 4 gut microbes significantly related to HOMA-IR. "*" means that P value is < 0.05.