Table 3.

Chromosome Aberrations in Different Subgroups of Uveal Melanoma (Full Sample, n = 314 Patients)

	Choroidal Melanoma (n = 217)	Ciliary Body Involved Melanoma (n = 97)
Variables	n (%)	n (%)	P Value	Adjusted P Value
Monosomy 3, n (%)
T1	12/40 (30)	5/11 (45.5)	0.336	0.584
T2	42/99 (42.4)	12/17 (70.6)	0.032	0.096
T3	29/70 (41.4)	38/57 (66.7)	0.005	0.020
T4	5/8 (62.5)	10/12 (83.3)	0.292	0.584
Chromosome 8q gain
T1	7/40 (17.5)	4/11 (36.4)	0.178	0.712
T2	34/99 (34.3)	7/17 (41.2)	0.586	0.759
T3	41/70 (58.6)	39/57 (68.4)	0.253	0.759
T4	6/8 (75)	11/12 (91.7)	0.306	0.759
Chromosome 8p loss
T1	3/40 (7.5)	1/11 (9.1)	0.862	1.000
T2	8/99 (8.1)	2/17 (11.8)	0.617	1.000
T3	16/70 (22.9)	8/57 (14)	0.207	0.828
T4	3/8 (37.5)	2/12 (16.7)	0.292	0.876
Chromosome 1p loss
T1	1/40 (2.5)	2/11 (18.2)	0.050	0.200
T2	14/99 (14.1)	3/17 (17.6)	0.706	1.000
T3	14/70 (20)	13/57 (22.8)	0.701	1.000
T4	3/8 (37.5)	3/12 (25)	0.550	1.000
Chromosome 6p gain
T1	6/40 (15)	2/11 (18.2)	0.797	1.000
T2	36/99 (36.4)	3/17 (17.6)	0.131	0.524
T3	28/70 (40)	17/57 (29.8)	0.233	0.699
T4	4/8 (50)	6/12 (50)	1.000	1.000
Metastasis
T1	1/40 (2.5)	2/11 (18.2)	0.050	0.200
T2	14/99 (14.1)	2/17 (11.8)	0.793	1.000
T3	16/70 (22.9)	20/57 (35.1)	0.128	0.384
T4	5/8 (62.5)	7/12 (58.3)	0.852	1.000

The P values were adjusted by the Holm–Bonferroni method.