Table 2.
Baseline biochemical parameters among three groups
| Parameter | Total (n=120) Mean±SD/% |
GROUP 1 (n=40) Mean±SD/% |
GROUP 2 (n=40) Mean±SD/% |
GROUP 3 (n=40) |
P Mean±SD/% |
|---|---|---|---|---|---|
| Hb (gm%) | 52.51±15.49 | 10.75±2.01 | 10.98±1.76 | 10.80±1.86 | 0.91 |
| Blood Urea (mg/dl) | 61.98±19.62 | 66.73±21.66 | 59.20±19.67 | 61.75±16.93 | 0.41 |
| S. Creatinine (mg/dl) | 2.14+0.63 | 2.28±0.75 | 2.13±0.61 | 2.10±0.71 | 0.52 |
| Calcium (mg/dl) | 8.86±0.88 | 9.03±0.77 | 8.68±1.19 | 8.85±0.70 | 0.41 |
| Phosphorus (mg/dl) | 4.27±0.74 | 4.28±0.64 | 4.40±0.90 | 4.28±0.64 | 0.92 |
| e-GFR (ml/min) | 34.37±11.84 | 32.55±10.41 | 34.80±13.02 | 35.80±12.02 | 0.49 |
| Sodium (mmol/l) | 138.49±4.22 | 138.73±3.84 | 138.30±3.99 | 138.35±4.92 | 0.93 |
| Potassium (mmol/l) | 4.38±0.56 | 4.43±0.64 | 4.40±0.59 | 4.38±0.59 | 0.95 |
| SGOT (U/L) | 24.33±11.25 | 22.30±9.15 | 23.30±6.82 | 42.58±104.01 | 0.58 |
| SGPT (U/L) | 23.35±13 | 20.23±10.48 | 22.65±8.73 | 41.38±97.18 | 0.06 |
| T. Protein (gm/dl) | 7.29±0.74 | 7.30±0.61 | 7.38±0.90 | 9.45±13.89 | 0.56 |
| Albumin (gm/dl) | 4.01±0.55 | 4.18±0.59 | 4.08±0.42 | 3.88±0.56 | 0.06 |
| ALP (U/L) | 94.75±39.90 | 92.15±38.38 | 96.60±34.39 | 95.58±46.76 | 0.45 |
| iPTH (pg/ml) | 321.78±301.56 | 269.33±178.19 | 269.50±160.91 | 288.15±167.14 | 0.75 |
| FGF23(pg/ml) | 17.86±23.28 | 16.13±13.44 | 18.15±27.12 | 19.35±27.03 | 0.77 |
| X RAY Abdomen | |||||
| Vascular calcification | 1 (2.5%) | 1 (2.5%) | 1 (2.5%) | 1.000 * | |
| X RAY Chest | |||||
| Vascular calcification | 0.0% | 1 (2.5%) | 1 (2.5%) | 0.795* | |
| 2 D Echocardiography | 0.367* | ||||
| LVH | 13 (32.5%) | 11 (27.5%) | 7 (17.5%) | ||
| LVEF <60% | 3 (7.5%) | 7 (17.5%) | 3 (7.5%) | ||
| Valvular calcification | 2 (5.0%) | 2 (5.0%) | 1 (2.5%) |
Data presented as mean±SD. Group 1- dietary phosphorus restriction, group 2- calcium based phosphate binders, group 3- non calcium based phosphate binders. BP: Blood Pressure; SGOT: serum glutamic oxaloacetictransaminasee; SGPT: serum glutamic pyruvic transaminase; ALP- alkaline phosphatase; iPTH: intact parathyroid hormone; FGF23: fibroblast growth factor 23, LVEF: left ventricular ejection fraction. Computed using KRUSKAL WALLIS TEST.