TABLE 4.

Average (±SD) HRF parameters in ROIs with positive signal change.

HRF parameter	Condition	T2DM	CNT	Statistics	Adjusted p-value
Peak amplitude	Thresh	0.098 ± 0.055	0.130 ± 0.035	1.592	0.177
	Submax	0.072 ± 0.039	0.113 ± 0.029	2.615	0.034
Peak latency	Thresh	7.500 ± 0.796	5.000 ± 1.054	−3.023	0.007
	Submax	7.500 ± 0.796	5.000 ± 1.054	−3.481	0.002
Relative slope to peak	Thresh	0.013 ± 0.008	0.032 ± 0.011	4.140	0.002
	Submax	0.010 ± 0.006	0.025 ± 0.008	4.720	0.001
AUC	Thresh	1.297 ± 0.450	1.413 ± 0.253	0.707	0.489
	Submax	1.007 ± 0.354	1.340 ± 0.218	2.537	0.037
APCS	Thresh	0.324 ± 0.155	0.492 ± 0.127	2.653	0.033
	Submax	0.254 ± 0.127	0.413 ± 0.090	3.217	0.012
fPCSA	Thresh	0.006 ± 0.006	0.128 ± 0.027	3.742	0.001
	Submax	0.004 ± 0.019	0.097 ± 0.022	3.756	0.001
sPCSA	Thresh	0.287 ± 0.160	0.340 ± 0.153	0.759	0.472
	Submax	0.206 ± 0.138	0.293 ± 0.113	1.551	0.182
tPCSA	Thresh	0.027 ± 0.023	0.004 ± 0.022	−1.323	0.219
	Submax	0.039 ± 0.032	0.013 ± 0.019	−1.935	0.083
ANCS	Thresh	0.364 ± 0.156	0.454 ± 0.130	1.401	0.218
	Submax	0.223 ± 0.101	0.394 ± 0.088	4.033	0.002
Initial dip area	Thresh	0.170 ± 0.077	0.121 ± 0.080	−1.403	0.218
	Submax	0.144 ± 0.073	0.110 ± 0.060	−1.140	0.292
Undershoot area	Thresh	0.194 ± 0.128	0.333 ± 0.067	3.047	0.002
	Submax	0.056 ± 0.061	0.284 ± 0.044	3.364	0.001

AUC, area under the curve; APCS, area of the positive curve section; fPCSA, first positive curve section area; sPCSA, second positive curve section area; tPCSA, third positive curve section area; ANCS, area of the negative curve section; Thresh, Threshold; Submax, Submaximum.