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. 2023 Jan 22;15(1):2164448. doi: 10.1080/19490976.2022.2164448

Table 1.

Beta diversity with respect to experimental, demographic, and mouse variables. Effect sizes and FDR corrected p-values of PERMANOVA tests between Bray-Curtis (Abundance and Activity) or Jaccard (Prevalence) distances and mouse characteristics, added sequentially in the final adonis models. Confounding variables were added sequentially in all models, in the order presented in the table from left to right, variables of interest were added independently in distinct models.

    Confounding variables
Variables of Interest
    Extraction Library Super Family Population Haplogroup Weight B4galnt2 Inflammation Score Inflammation Prevalence
Abundance (DNA) effect size 12.03% 1.67% 7.48% 9.23% 2.52% 0.83% 0.93% 0.77% 0.44%
p-value 0.0001 0.0022 0.0002 0.0001 0.0532 0.0198 0.8272 0.1715 0.8272
Activity (RNA) effect size 12.68% 1.38% 7.29% 8.57% 2.54% 0.67% 1.00% 0.87% 0.60%
p-value 0.0001 0.0305 0.0007 0.0007 0.0409 0.1034 0.6867 0.0465 0.4153
Prevalence effect size 12.57% 1.52% 7.72% 8.85% 2.58% 0.73% 0.98% 0.84% 0.47%
p-value 0.0001 0.0108 0.0003 0.0003 0.0282 0.0372 0.7960 0.0555 0.7960