Table 1.
Demographic and Clinical Characteristics.
| Study 1 b | Study 2 b | |||||
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| Placebo | Prazosin | |||||
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| n=45 | n=13 | n=10 | ||||
| N | % | N | % | N | % | |
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| Gender – no. of males | 31 | 68.9% | 10 | 76.9% | 6 | 60.0% |
| Race | ||||||
| Caucasian | 25 | 55.6% | 8 | 61.5% | 7 | 70.0% |
| African American | 16 | 35.6% | 5 | 38.5% | 3 | 30.0% |
| Other | 4 | 8.9% | 0 | 0% | 0 | 0.0% |
| No. of regular smokers | 24 | 53.3% | 7 | 53.8% | 4 | 40.0% |
| Stabilized on antidepressants | 2 | 4.4% | 0 | 0.0% | 0 | 0.0% |
| Lifetime depression - % | 11 | 24.4% | 3 | 23.1% | 3 | 30.0% |
| Lifetime anxiety (incl. PTSD) - % | 12 | 26.7% | 7 | 53.8% | 5 | 50.0% |
| Lifetime anxiety (without PTSD) - % | 6 | 13.3% | 3 | 23.1% | 2 | 20.0% |
| M | SD | M | SD | M | SD | |
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| Age a | 38.33 | 11.15 | 41.92 | 9.84 | 39.10 | 10.65 |
| Years of Education a | 13.73 | 2.22 | 13.62 | 1.56 | 13.00 | 2.40 |
| Years of alcohol use a | 14.69 | 10.63 | 16.54 | 10.29 | 13.90 | 7.68 |
| Past 30 days alcohol use a | 18.73 | 8.27 | 17.69 | 7.09 | 21.80 | 8.78 |
| Ave Drinks/Day | 3.69 | 2.75 | 4.13 | 3.22 | 5.53 | 2.88 |
| % Drinking Days | 61.74 | 31.09 | 54.05 | 30.45 | 74.60 | 21.16 |
| % Heavy Drinking Days | 36.16 | 31.91 | 42.62 | 31.23 | 49.21 | 28.67 |
| CIWA Total Score a | 4.41 | 4.69 | 3.46 | 4.70 | 5.2 | 5.96 |
a
Data indicate means and standard deviations. All variables: p>.05.
b
All participants met criteria for current Alcohol Use Disorders (AUD) as defined by the Diagnostic and Statistical Manual (DSM-IV-TR; DSM-5) as determined via the Standard Clinical Interview for DSM-IV (SCID). Alcohol withdrawal (AW) symptoms were assessed by the Clinical Institute of Withdrawal Assessment – Alcohol Revised (CIWA-Ar).